Endocrine Abstracts

Background: Melatonin as strong antioxidant and free radical scavenger can play important, protective role in disease in which oxidative damage is a significant component e.g.: in coronary heart disease, neoplastic disease, neurodegenerative disease. The aim of our study was determination of the effect of melatonin supplementation on malonyldialdehyde (MDA) concentration and activity of: superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) in patients...

Introduce: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma (DTC) is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. In patients with elevated thyroglobulin levels and with no evidence of disease on radioiodine scintigraphy, scintigraphy with somatostatin analogs can be an alternative imaging modality.The aim: Assessment of scintigraphy with the somatostatin analog 99mTc-HYNIC-TATE to visu...

Introduction: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. DOTA-TATE preparation is a somatostatin analogue coupled with 90 Y which emites β (−) radiation. Its use in a treatment depends on excessive expression of somatostatin receptors (SSTR) in malignant tumours.The aim of the study: To present a possibility of treatment o...